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The gut microbiome-metabolome dataset collection: a curated resource for integrative meta-analysis.

Abstract

Integrative analysis of microbiome and metabolome data obtained from human fecal samples is a promising avenue for better understanding the interplay between bacteria and metabolites in the human gut, in both health and disease. However, acquiring, processing, and unifying such datasets from multiple sources is a daunting and challenging task. Here we present a publicly available, simple-to-use, curated dataset collection of paired fecal microbiome-metabolome data from multiple cohorts. This data resource allows researchers to easily obtain multiple fully processed and integrated microbiome-metabolome datasets, facilitating the discovery of universal microbe-metabolite links, benchmark various microbiome-metabolome integration tools, and compare newly identified microbe-metabolite findings to other published datasets.

Year of Publication
2022
Journal
NPJ Biofilms Microbiomes
Volume
8
Issue
1
Number of Pages
79
Date Published
2022 Oct 15
ISSN Number
2055-5008
DOI
10.1038/s41522-022-00345-5
Alternate Journal
NPJ Biofilms Microbiomes
PMCID
PMC9569371
PMID
36243731
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The Dog Aging Project is supported by U19 grant AG057377 from the National Institute on Aging, a part of the National Institutes of Health, and by private donations.
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